Glucagon-like peptide 1 (GLP-1) [7-36] is an incretion hormone, which has been shown to stimulate secretion of insulin in the presence of elevated blood glucose concentrations, but not during periods of low blood glucose concentrations (hypoglycemia). It exhibits several anti-diabetic actions,and is now in phase 3 Clinical trial.Huayi Bio-Lab has succeeded in establishing large-scale production of rhGLP-1(7-36). is seeking for a partner to develop the peptide in a global market.

Exendin-4 is a 39-amino acid peptide that exhibits anti-diabetic actions of the mammalian hormone glucagon-like peptide (GLP-1). In comparison with GLP-1 it has also been demonstrated to have a longer half-life and lower therapeutical concentration. Huayi Bio-LAB also has one novel Exendin-4 analog candidate in preclinical research. The Chinese patent covering this exendin-4 derivative has been granted in 2005. US and worldwide patent applications have been granted in 2008.

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